Eloise Hudry

Eloise Hudry

Company: NIBR

Job title: Associate Director, Preclinical Safety, Cell & Gene Therapy


Describing AAV-Driven Safety Findings (Depatotoxicity & Peripheral Neuropathy) in the Non-Human Primate & Potential Translatability 9:30 am

Outlining the future of preclinical development: Is in vivo modelling on the way out? Presentation of retrospectively analyzed data from preclinical non-human primate (NHP) studies to establish the time course of self-complementary AAV9(scAAV9)-related toxicology findings after systemic or intrathecal administration. Investigation of the potential triggers (capsid versus transgene) for such toxicities in the cynomolgus macaque, the…Read more

day: Conference Day Two

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