Translation of Gene Therapy Brain Biomarkers from Nonclinical Science to Clinical Trials: A Case Study in Canavan Disease
Time: 2:30 pm
day: Clinical Stream Day 1 PM
Details:
- MRI and MRS evaluations of candidate biomarkers
- Preclinical assessments in a murine model
- Clinical evidence by magnetic resonance spectroscopy in humans by standardized spectrum analyses
- Potential uses in clinical trials to support regulatory activities
