Smitha Jagadish

Smitha Jagadish

Company: Sanofi

Job title: Lab Head

Seminars:

Gene Therapy for Glut1 Deficiency Syndrome: Upregulation of Cerebral Glucose at the Blood-Brain Barrier 1:30 pm

Glucose transporter 1 Deficiency Syndrome (Glut1 DS) is a neurodevelopmental genetic disorder caused by haploinsufficiency of SLC2A1 gene encoding Glut1 There is currently a high unmet need for a long-term therapy that does not bypass the utilization of glucose as an energy source in the brain Demonstrating that rAAV9 mediated delivery of Glut1 in neonatal…Read more

day: Day One

Q&A Panel Discussion: Vector Engineering & Selection 2:20 pm

• How do you choose the vector? Optimal • Engineer the vector? • Reviewing vectors suitable for CNS targets • Discussing vector library data • Evaluating promoter choicesRead more

day: Day One

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