Showcasing the Latest CNS Toxicity Knowledge After Direct Parenchymal Administration
Time: 5:30 pm
day: Day One
Details:
- Assessing the delivery procedure: risks and improvements
- Exploring local toxicity and AAV capsids, and transgene expression
- MRI follow-up and evaluation of local tolerance: experience from large animals studies and patients
- Evaluating the immune reaction and redosing strategies
- Next steps: disease selection and protocol design
