Improving Neuronal Gene Transfer to the Brain After CSF Administration of AAV9 in Large Animal Models

Time: 12:00 pm
day: Day One: Track B AM

Details:

  • Biodistribution results will be presented from studies carried out in juvenile NHP and pig models
  • Comparison of lumbar IT vs ICM delivery routes as well as constitutive vs neuronal specific promoters in NHP
  • Optimization of factors such as dose volume, flush volume, and physical positioning

Speakers: