Gene Therapy for the Treatment of Autosomal Dominant Alzheimer’s Disease
Time: 8:00 am
day: Day Two
Details:
- The role of presenilin in ADAD and rationale for a gene replacement approach
- Preclinical proof-of-principle data in mouse models and human-derived ADAD mutation-bearing cell lines
- Evaluating expression and biodistribution in nonhuman primates
- Phase 1/2 clinical trial plans
